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1

A calculator program for clinical application of the Bayesian method of predicting plasma drug levels

Stefano Ruffo, Andrea Messori, Thaddeus H. Grasela, Giovanni Longo, Giancarlo Donati-Cori, Marzia Matucci, Massimo Morfini, Enrico Tendi

Journal:

Computer Programs in Biomedicine

Year:

1985

Language:

english

File:

PDF, 764 KB

english, 1985

2

Model-Informed Drug Development for Malaria Therapeutics

Andrews, Kayla Ann, Wesche, David, McCarthy, James, Möhrle, Jörg j., Tarning, Joel, Phillips, Luann, Kern, Steven, Grasela, Thaddeus

Journal:

Annual Review of Pharmacology

Year:

2018

Language:

english

File:

PDF, 771 KB

english, 2018

3

Experience with Nonmem: Analysis of Routine Phenytoin Clinical Pharmacokinetic Data

Sheiner, Lewis B., Grasela, Thaddeus H.

Journal:

Drug Metabolism Reviews

Year:

1984

Language:

english

File:

PDF, 498 KB

english, 1984

4

Population pharmacokinetics and pharmacokinetics/pharmacodynamics of bendamustine in pediatric patients with relapsed/refractory acute leukemia

Darwish, Mona, Megason, Gail, Bond, Mary, Hellriegel, Edward, Robertson, Philmore, Grasela, Thaddeus, Phillips, Luann

Journal:

Current Medical Research and Opinion

Year:

2014

Language:

english

File:

PDF, 783 KB

english, 2014

5

Relationship between drug exposure and the efficacy and safety of bupropion sustained release for smoking cessation

Johnston, J. Andrew, Fiedler-Kelly, Jill, Glover, Elbert D., Sachs, David P. L., Grasela, Thaddeus H., DeVeaugh-Geiss, Joseph

Journal:

Nicotine & Tobacco Research

Year:

2001

Language:

english

File:

PDF, 299 KB

english, 2001

6

Pharmacokinetics in clinical practice. By David J. Greenblatt, M. D. and Richard I. Shader, M.D. W. B. Saunders Company, Philadelphia. 1985. 144 pp. 15 × 25 cm. ISBN 0-72-161148-6. $18.95

Thaddeus H. Grasela Jr.

Journal:

Journal of Pharmaceutical Sciences

Year:

1986

Language:

english

File:

PDF, 279 KB

english, 1986

7

An evaluation of population pharmacokinetics in therapeutic trials. Part I. Comparison of methodologies

Grasela, Thaddeus H, Antai, Edward J, Townsend, Raymond J, Smith, Randall B

Journal:

Clinical Pharmacology & Therapeutics

Year:

1986

Language:

english

File:

PDF, 638 KB

english, 1986

8

An evaluation of population pharmacokinetics in therapeutic trials. Part II. Detection of a drug-drug interaction

Grasela, Thaddeus H, Antal, Edward J, Ereshefsky, Larry, Wells, Barbara G, Evans, R Lee, Smith, Randall B

Journal:

Clinical Pharmacology & Therapeutics

Year:

1987

Language:

english

File:

PDF, 730 KB

english, 1987

9

An evaluation of population pharmacokinetics in therapeutic trials. Part III. Prospective data collection versus retrospective data assembly

Antal, Edward J, Grasela, Thaddeus H, Smith, Randall B

Journal:

Clinical Pharmacology & Therapeutics

Year:

1989

Language:

english

File:

PDF, 626 KB

english, 1989

10

Population pharmacodynamics of doxacurium

Schmith, Virginia D, Fiedler-Kelly, Jill, Abou-Donia, Martha, Huffman, Cameron S, Grasela, Thaddeus H

Journal:

Clinical Pharmacology & Therapeutics

Year:

1992

Language:

english

File:

PDF, 1.08 MB

english, 1992

11

Evaluation of population pharmacokinetics in therapeutic trials. IV. Application to postmarketing surveillance

DeVane, C Lindsay, Grasela, Thaddeus H, Antal, Edward J, Miller, Ronald L

Journal:

Clinical Pharmacology & Therapeutics

Year:

1993

Language:

english

File:

PDF, 632 KB

english, 1993

12

Reply

Schmith, Virginia D, Fiedler-Kelly, Jill, Grasela, Thaddeus H

Journal:

Clinical Pharmacology & Therapeutics

Year:

1994

Language:

english

File:

PDF, 562 KB

english, 1994

13

Prospective Use of Population Pharmacokinetics/ Pharmacodynamics in the Development of Cisatracurium

Virginia D. Schmith, Jill Fiedler-Kelly, Luann Phillips, Thaddeus H. Grasela

Journal:

Pharmaceutical Research

Year:

1997

File:

PDF, 531 KB

1997

14

Population Pharmacokinetics of Tirilazad: Effects of Weight, Gender, Concomitant Phenytoin, and Subarachnoid Hemorrhage

Joseph C. Fleishaker, Jill Fiedler-Kelly, Thaddeus H. Grasela

Journal:

Pharmaceutical Research

Year:

1999

File:

PDF, 1.45 MB

1999

15

Informatics: The fuel for pharmacometric analysis

Thaddeus H. Grasela, Jill Fiedler-Kelly, Brenda Cirincione, Darcy Hitchcock, Kathleen Reitz, Susanne Sardella, Barry Smith

Journal:

The AAPS Journal

Year:

2007

Language:

english

File:

PDF, 446 KB

english, 2007

16

Symptomatic Cardiotoxicity Associated with 5-Fluorouracil

Dr. Christine C. Meyer, Dr. Karim Anton Calis, Ms. Laurie B. Burke, Ms. Cynthia A. Walawander, Dr. Thaddeus H. Grasela

Journal:

Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy

Year:

1997

Language:

english

File:

PDF, 742 KB

english, 1997

17

The population pharmacokinetics of theophylline in neonates and young infants

Emory S. Moore, Roger G. Faix, Raul C. Banagale, Thaddeus H. Grasela

Journal:

Journal of Pharmacokinetics and Pharmacodynamics

Year:

1989

Language:

english

File:

PDF, 1.14 MB

english, 1989

18

An evaluation of point and interval estimates in population pharmacokinetics using Nonmem analysis

Donald B. White, Cynthia A. Walawander, Ying Tung, Thaddeus H. Grasela

Journal:

Journal of Pharmacokinetics and Pharmacodynamics

Year:

1991

Language:

english

File:

PDF, 1.65 MB

english, 1991

19

Evaluation of hypothesis testing for comparing two populations using NONMEM analysis

Donald B. White, Cynthia A. Walawander, Dong Y. Liu, Thaddeus H. Grasela

Journal:

Journal of Pharmacokinetics and Pharmacodynamics

Year:

1992

Language:

english

File:

PDF, 1.08 MB

english, 1992

20

The application of population pharmacokinetic analysis to large scale clinical efficacy trials

Edward J. Antal, Thaddeus H. Grasela, Randall B. Smith

Journal:

Journal of Pharmacokinetics and Pharmacodynamics

Year:

1991

Language:

english

File:

PDF, 484 KB

english, 1991

21

Pharmacostatistical modeling for observational data

Thaddeus H. Grasela, Lewis B. Sheiner

Journal:

Journal of Pharmacokinetics and Pharmacodynamics

Year:

1991

Language:

english

File:

PDF, 656 KB

english, 1991

22

An introduction to mixed effect modeling: Concepts, definitions, and justification

Lewis B. Sheiner, Thaddeus H. Grasela

Journal:

Journal of Pharmacokinetics and Pharmacodynamics

Year:

1991

Language:

english

File:

PDF, 840 KB

english, 1991

23

A multi-center study to evaluate the pharmacokinetic and clinical interactions between alprazolam and imipramine

Edward J. Antal, Thaddeus H. Grasela, Larry Ereshefsky, Barbara G. Wells, R. Lee Evans, Randall B. Smith

Journal:

Journal of Pharmacokinetics and Pharmacodynamics

Year:

1991

Language:

english

File:

PDF, 424 KB

english, 1991

24

Pharmacokinetic/pharmacodynamic profile for tigecycline—a new glycylcycline antimicrobial agent

Alison K. Meagher, Paul G. Ambrose, Thaddeus H. Grasela, Evelyn J. Ellis-Grosse

Journal:

Diagnostic Microbiology and Infectious Disease

Year:

2005

Language:

english

File:

PDF, 190 KB

english, 2005

25

Exposure–response analyses of tigecycline tolerability in healthy subjects

Julie Passarell, Elizabeth Ludwig, Kathryn Liolios, Alison K. Meagher, Thaddeus H. Grasela, Timothy Babinchak, Evelyn J. Ellis-Grosse

Journal:

Diagnostic Microbiology and Infectious Disease

Year:

2009

Language:

english

File:

PDF, 611 KB

english, 2009

26

Population pharmacokinetics of (R)-albuterol and (S)-albuterol in pediatric patients aged 4–11 years with asthma

Gary Maier, Christopher Rubino, Roger Hsu, Thaddeus Grasela, Rudolf A. Baumgartner

Journal:

Pulmonary Pharmacology & Therapeutics

Year:

2007

Language:

english

File:

PDF, 323 KB

english, 2007

27

Kinetics and action of N-methylthiotetrazole in volunteers and patients: Population-based clinical comparisons of antibiotics with and without this moiety

Jerome J. Schentag, Lynda S. Welage, James S. Williams, John H. Wilton, Martin H. Adelman, David Rigan, Thaddeus H. Grasela

Journal:

The American Journal of Surgery

Year:

1988

Language:

english

File:

PDF, 524 KB

english, 1988

28

Efficacy of theophylline for prevention of post-extubation respiratory failure in very low birth weight infants

Rose M. Viscardi, Roger G. Faix, Joanne J. Nicks, Thaddeus H. Grasela

Journal:

The Journal of Pediatrics

Year:

1985

Language:

english

File:

PDF, 321 KB

english, 1985

29

A randomized, controlled trial of parenteral clindamycin in neonatal necrotizing enterocolitis

Roger G. Faix, Theodore Z. Polley, Thaddeus H. Grasela

Journal:

The Journal of Pediatrics

Year:

1988

Language:

english

File:

PDF, 633 KB

english, 1988

30

Challenges in the transition to model-based development

Thaddeus H. Grasela, Jill Fiedler-Kelly, Cynthia A. Walawander, Joel S. Owen, Brenda B. Cirincione, Kathleen E. Reitz, Elizabeth A. Ludwig, Julie A. Passarell, Charles W. Dement

Journal:

The AAPS Journal

Year:

2005

Language:

english

File:

PDF, 649 KB

english, 2005

31

Population Pharmacokinetics of Lamotrigine Adjunctive Therapy in Adults with Epilepsy

Grasela, Thaddeus H., Fiedler-Kelly, Jill, Cox, Eugène, Womble, Gilda P., Risner, Marcus E., Chen, Chao

Journal:

Journal of Clinical Pharmacology

Year:

1999

Language:

english

File:

PDF, 616 KB

english, 1999

32

The Cost-Effectiveness of Cefepime plus Metronidazole versus Imipenem/Cilastatin in the Treatment of Complicated Intra-Abdominal Infection

Barie, Philip S., Rotstein, Ori D., Dellinger, E. Patchen, Grasela, Thaddeus H., Walawander, Cynthia A.

Journal:

Surgical Infections

Year:

2004

Language:

english

File:

PDF, 306 KB

english, 2004

33

Implementation of a Nursing Home Urinary Incontinence Management Program With and Without Tolterodine

Ouslander, Joseph G., Maloney, Cynthia, Grasela, Thaddeus H., Rogers, Lucy, Walawander, Cynthia A.

Journal:

Journal of the American Medical Directors Association

Year:

2001

Language:

english

File:

PDF, 152 KB

english, 2001

34

Applying Epidemiology-Based Outcomes Research to Clinical Decision-Making

Dr Edward C. Y. Wang,Thaddeus H. Grasela,Cynthia A. Walawander

Journal:

PharmacoEconomics

Year:

1999

Language:

english

File:

PDF, 116 KB

english, 1999

35

Population Pharmacokinetics of Procainamide from Routine Clinical Data

Thaddeus H. Grasela,Professor Lewis B. Sheiner

Journal:

Clinical Pharmacokinetics

Year:

1984

Language:

english

File:

PDF, 974 KB

english, 1984

36

Population Pharmacokinetic Analysis of Linezolid in Patients With Infectious Disease: Application to Lower Body Weight and Elderly Patients

Abe, Sadahiro, Chiba, Koji, Cirincione, Brenda, Grasela, Thaddeus H., Ito, Kaori, Suwa, Toshio

Journal:

Journal of Clinical Pharmacology

Year:

2009

Language:

english

File:

PDF, 1004 KB

english, 2009

37

Kerfuffle!

Grasela, Thaddeus H., Ludwig, Elizabeth, Fiedler-Kelly, Jill

Journal:

Journal of Clinical Pharmacology

Year:

2009

Language:

english

File:

PDF, 78 KB

english, 2009

38

The Pharmacokinetic and Pharmacodynamic Profile of Tigecycline

Meagher, Alison K., Ambrose, Paul G., Grasela, Thaddeus H., Ellis‐Grosse, Evelyn J.

Journal:

Clinical Infectious Diseases

Year:

2005

Language:

english

File:

PDF, 326 KB

english, 2005

39

An Evaluation of the Quinolone-Theophylline Interaction Using the Food and Drug Administration Spontaneous Reporting System

Grasela, Thaddeus H.

Journal:

Archives of Internal Medicine

Year:

1992

Language:

english

File:

PDF, 712 KB

english, 1992

40

Dose Proportionality of Cisatracurium

Schmith, Virginia D., Fiedler-Kelly, Jill, Phillips, Luann, Grasela, Thaddeus H.

Journal:

Journal of Clinical Pharmacology

Year:

1997

Language:

english

File:

PDF, 779 KB

english, 1997

41

Population Pharmacokinetic Analysis of Didanosine (2′,3′-Dideoxyinosine) Plasma Concentrations Obtained in Phase I Clinical Trials in Patients with AIDS or AIDS-Related Complex

Pai, Sudhakar M., Shukla, Umesh A., Grasela, Thaddeus H., Knupp, Catherine A., Dolin, Raphael, Valentine, Fred T., McLaren, Colin, Liebman, Howard A., Martin, Russell R., Pittman, Kenneth A., Barbhaiy

Journal:

Journal of Clinical Pharmacology

Year:

1992

Language:

english

File:

PDF, 989 KB

english, 1992

42

Eliminating Intensive Postoperative Care in Same-day Surgery Patients Using Short-acting Anesthetics

Apfelbaum, Jeffrey L., Walawander, Cynthia A., Grasela, Thaddeus H., Wise, Phillip, McLeskey, Charles, Roizen, Michael F., Wetchler, Bernard V., Korttila, Kari

Journal:

Year:

2002

Language:

english

File:

PDF, 479 KB

english, 2002

43

The Publication of Commercially Supported Supplements Statement

Roizen, Michael F., Apfelbaum, Jeffrey L., Grasela, Thaddeus H., Hug, Carl C., McLeskey, Charles H., Nahrwold, Michael L., Stanley, Theodore H., Thisted, Ronald A., Walawander, Cynthia A., White, Paul

Journal:

Anesthesia & Analgesia

Year:

1995

Language:

english

File:

PDF, 662 KB

english, 1995

44

The Publication of Commercially Supported Supplements Statement

Roizen, Michael F., Apfelbaum, Jeffrey L., Grasela, Thaddeus H., Hug, Carl C., McLeskey, Charles H., Nahrwold, Michael L., Stanley, Theodore H., Thisted, Ronald A., Walawander, Cynthia A., White, Paul

Journal:

Anesthesia & Analgesia

Year:

1995

Language:

english

File:

PDF, 662 KB

english, 1995

45

Analysis of Potential Risk Factors Associated with the Development of Pancreatitis in Phase I Patients with AIDS or AIDS-Related Complex Receiving Didanosine

Thaddeus H. Grasela, Cynthia A. Walawander, Mohan Beltangady, Catherine A. Knupp, Russell R. Martin, Lisa M. Dunkle, Rashmi H. Barbhaiya, Kenneth A. Pittman, Raphael Dolin, Fred T. Valentine and Howar

Journal:

The Journal of Infectious Diseases

Year:

1994

Language:

english

File:

PDF, 1.12 MB

english, 1994

46

Pretreatment Regimens for Adverse Events Related to Infusion of Amphotericin B

S. Diane Goodwin, John D. Cleary, Cynthia A. Walawander, Jerry W. Taylor and Thaddeus H. Grasela, Jr.

Journal:

Clinical Infectious Diseases

Year:

1995

Language:

english

File:

PDF, 450 KB

english, 1995

47

Use of Antifungal Therapy in Hospitalized Patients I. Results Prior to the Marketing of Fluconazole

Hartzema, Abraham G., Porta, Miquel S., Tilson, Hugh H., Grasela, Thaddeus H., Goodwin, S. Diane, Pasko, Mary T., Walawander, Cynthia A., Raebel, Marsha A.

Journal:

Annals of Pharmacotherapy

Year:

1994

Language:

english

File:

PDF, 1.65 MB

english, 1994

48

Clinical and Economic Impact of Oral Ciprofloxacin as Follow-up to Parenteral Antibiotics

Hartzema, Abraham G., Porta, Miquel S., Tilson, Hugh H., Grasela, Thaddeus H., Paladino, Joseph A., Schentag, Jerome J., Huepenbecker, Dawn, Rybacki, James, Purcell, Jeffrey B., Fiedler, Jill B.

Journal:

Year:

1991

Language:

english

File:

PDF, 1.14 MB

english, 1991

49

NONMEM: AN ALTERNATIVE TO TRADITIONAL PHARMACOKINETIC STUDIES IN PEDIATRIC POPULATIONS

Grasela, Thaddeus H, Donn, Steven M

Journal:

Pediatric Research

Year:

1984

Language:

english

File:

PDF, 148 KB

english, 1984

50

POPULATION PHARMACOKINETICS OF PHENOBARBITAL IN NEWBORNS DETERMINED BY NONMEM ANALYSIS

Grasela, Thaddeus H, Donn, Steven M

Journal:

Pediatric Research

Year:

1984

Language:

english

File:

PDF, 148 KB

english, 1984